UBAC1 antibody (AA 91-140)

Catalog No. ABIN1535446

The Rabbit Polyclonal anti-UBAC1 antibody is suitable to detect UBAC1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for UBAC1 antibody (AA 91-140) (ABIN1535446)

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBAC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-UBAC1 Antibody

Binding Specificity: AA 91-140

Purpose: GBDR1 Antibody

Specificity: GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for UBAC1

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Alternative Name: UBAC1

Background:

Synonyms: UBAC1, GBDR1, KPC2, UBADC1, Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting com

Background: function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification, protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

Gene Name: UBAC1

Protein Name: Ubiquitin-associated domain-containing protein 1

Molecular Weight: 45 kDa

Gene ID: 10422

OMIM: 608129

UniProt: Q9BSL1