PLAGL1 antibody (AA 311-360)

Catalog No. ABIN1535506

The Rabbit Polyclonal anti-PLAGL1 antibody is suitable to detect PLAGL1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PLAGL1 antibody (AA 311-360) (ABIN1535506)

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLAGL1 Antibody

Binding Specificity: AA 311-360

Purpose: ZAC1 Antibody

Specificity: ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLAGL1

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Alternative Name: PLAGL1

Background:

Synonyms: PLAGL1, LOT1, ZAC, Zinc finger protein PLAGL1, Lost on transformation 1, LOT-1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZAC

Background: This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],

Gene Name: PLAGL1

Protein Name: Zinc finger protein PLAGL1

Molecular Weight: 50 kDa

Gene ID: 5325

OMIM: 603044

UniProt: Q9UM63