Serotonin Receptor 5A antibody (AA 15-64)

Catalog No. ABIN1535556

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 5A in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Serotonin Receptor 5A antibody (AA 15-64) (ABIN1535556)

Target: Serotonin Receptor 5A (HTR5A) (5-Hydroxytryptamine (Serotonin) Receptor 5A (HTR5A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 5A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Serotonin Receptor 5A Antibody

Binding Specificity: AA 15-64

Purpose: SR-5A Antibody

Specificity: SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Serotonin Receptor 5A

Target: Serotonin Receptor 5A (HTR5A) (5-Hydroxytryptamine (Serotonin) Receptor 5A (HTR5A))

Alternative Name: HTR5A

Background:

Synonyms: HTR5A, 5-hydroxytryptamine receptor 5A, 5-HT-5, 5-HT-5A, 5-HT5A, Serotonin receptor 5A

Background: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],

Gene Name: HTR5A

Protein Name: 5-hydroxytryptamine receptor 5A

Molecular Weight: 40 kDa

Gene ID: 3361

OMIM: 601305

UniProt: P47898

Pathways: JAK-STAT Signaling