FZD3 antibody (AA 141-190)

Catalog No. ABIN1535610

This Rabbit Polyclonal antibody specifically detects FZD3 in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for FZD3 antibody (AA 141-190) (ABIN1535610)

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-FZD3 Antibody

Binding Specificity: AA 141-190

Purpose: Frizzled-3 Antibody

Specificity: Frizzled-3 Polyclonal Antibody detects endogenous levels of Frizzled-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FZD3. AA range:141-190

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FZD3

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Alternative Name: FZD3

Background:

Synonyms: FZD3, Frizzled-3, Fz-3, hFz3

Background: frizzled class receptor 3(FZD3) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010],

Gene Name: FZD3

Protein Name: Frizzled-3

Molecular Weight: 76 kDa

Gene ID: 7976

OMIM: 606143

UniProt: Q9NPG1

Pathways: WNT Signaling, Tube Formation