CHRM1 antibody (AA 295-344)

Catalog No. ABIN1535644

The Rabbit Polyclonal anti-CHRM1 antibody is suitable to detect CHRM1 in samples from Rat, Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for CHRM1 antibody (AA 295-344) (ABIN1535644)

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHRM1 Antibody

Binding Specificity: AA 295-344

Purpose: mAChR M1 Antibody

Specificity: MAChR M1 Polyclonal Antibody detects endogenous levels of mAChR M1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CHRM1. AA range:295-344

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Alternative Name: CHRM1

Background:

Synonyms: CHRM1, Muscarinic acetylcholine receptor M1

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008],

Gene Name: CHRM1

Protein Name: Muscarinic acetylcholine receptor M1

Molecular Weight: 51 kDa

Gene ID: 1128

OMIM: 118510

UniProt: P11229

Pathways: Synaptic Membrane