CHRM4 antibody (AA 236-285)

Catalog No. ABIN1535646

This Rabbit Polyclonal antibody specifically detects CHRM4 in WB, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CHRM4 antibody (AA 236-285) (ABIN1535646)

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CHRM4 Antibody

Binding Specificity: AA 236-285

Purpose: mAChR M4 Antibody

Specificity: MAChR M4 Polyclonal Antibody detects endogenous levels of mAChR M4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CHRM4. AA range:236-285

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHRM4

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Alternative Name: CHRM4

Background:

Synonyms: CHRM4, Muscarinic acetylcholine receptor M4

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008],

Gene Name: CHRM4

Protein Name: Muscarinic acetylcholine receptor M4

Molecular Weight: 53 kDa

Gene ID: 1132

OMIM: 118495

UniProt: P08173

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane