MRGPRX1 antibody (AA 271-320)

Catalog No. ABIN1535777

The Rabbit Polyclonal anti-MRGPRX1 antibody (ABIN1535777) specifically detects MRGPRX1 in WB and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MRGPRX1 antibody (AA 271-320) (ABIN1535777)

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MRGPRX1 Antibody

Binding Specificity: AA 271-320

Purpose: MRGX1 Antibody

Specificity: MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRGPRX1

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Alternative Name: MRGX1

Background:

Synonyms: MRGPRX1, MRGX1, SNSR3, SNSR4, Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4

Background: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,

Gene Name: MRGPRX1

Protein Name: Mas-related G-protein coupled receptor member X1

Molecular Weight: 36 kDa

Gene ID: 259249

OMIM: 607227

UniProt: Q96LB2