TACR1 antibody (AA 211-260)

Catalog No. ABIN1535783

The Rabbit Polyclonal anti-TACR1 antibody (ABIN1535783) specifically detects TACR1 in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for TACR1 antibody (AA 211-260) (ABIN1535783)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TACR1 Antibody

Binding Specificity: AA 211-260

Purpose: NK-1R Antibody

Specificity: NK-1R Polyclonal Antibody detects endogenous levels of NK-1R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NK1R. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Alternative Name: NK1R

Background:

Synonyms: TACR1, NK1R, TAC1R, Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1

Background: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions.This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008],

Gene Name: TACR1

Protein Name: Substance-P receptor

Molecular Weight: 46 kDa

Gene ID: 6869

OMIM: 162323

UniProt: P25103

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration