NPY1R antibody (AA 221-270)

Catalog No. ABIN1535788

The Rabbit Polyclonal anti-NPY1R antibody is suitable to detect NPY1R in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for NPY1R antibody (AA 221-270) (ABIN1535788)

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NPY1R Antibody

Binding Specificity: AA 221-270

Purpose: NPY1-R Antibody

Specificity: NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY1R. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Alternative Name: NPY1R

Background:

Synonyms: NPY1R, NPYR, NPYY1, Neuropeptide Y receptor type 1, NPY1-R

Background: This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013],

Gene Name: NPY1R

Protein Name: Neuropeptide Y receptor type 1

Molecular Weight: 44 kDa

Gene ID: 4886

OMIM: 162641

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour