Prokineticin Receptor 1 antibody (AA 19-68)

Catalog No. ABIN1535984

The Rabbit Polyclonal anti-Prokineticin Receptor 1 antibody (ABIN1535984) specifically detects Prokineticin Receptor 1 in ELISA, WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Prokineticin Receptor 1 antibody (AA 19-68) (ABIN1535984)

Target: Prokineticin Receptor 1 (PROKR1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prokineticin Receptor 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Prokineticin Receptor 1 Antibody

Binding Specificity: AA 19-68

Purpose: PKR1 Antibody

Specificity: PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PKR1. AA range:19-68

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, IF ICC 1:100-500,ELISA 1:5000-20000,IHC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Alternative Name: PKR1

Background:

Synonyms: PROKR1, GPR73, PKR1, Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73a

Background: prokineticin receptor 1(PROKR1) Homo sapiens This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016],

Gene Name: PROKR1

Protein Name: Prokineticin receptor 1

Molecular Weight: 44 kDa

Gene ID: 10887

OMIM: 607122

UniProt: Q8TCW9

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma