AVPR1B antibody (AA 275-324)

Catalog No. ABIN1536013

The Rabbit Polyclonal anti-AVPR1B antibody is suitable to detect AVPR1B in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for AVPR1B antibody (AA 275-324) (ABIN1536013)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-AVPR1B Antibody

Binding Specificity: AA 275-324

Purpose: AVP Receptor V3 Antibody

Specificity: AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: AVPR1B

Background:

Synonyms: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

Gene Name: AVPR1B

Protein Name: Vasopressin V1b receptor

Molecular Weight: 46 kDa

Gene ID: 553

OMIM: 600264

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones