Ephrin A2 antibody (Cleaved-Asn188)

Catalog No. ABIN1536129

This Rabbit Polyclonal antibody specifically detects Ephrin A2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Ephrin A2 antibody (Cleaved-Asn188) (ABIN1536129)

Target: Ephrin A2 (EFNA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ephrin A2 Antibody

Binding Specificity: AA 139-188, Cleaved-Asn188

Purpose: Cleaved-Ephrin-A2 (N188) Antibody

Specificity: Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Ephrin A2

Target: Ephrin A2 (EFNA2)

Alternative Name: EFNA2

Background:

Synonyms: EFNA2, EPLG6, LERK6, Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L

Background: This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],

Gene Name: EFNA2

Protein Name: Ephrin-A2

Molecular Weight: 21 kDa

Gene ID: 1943

OMIM: 602756

UniProt: O43921