TGM4 antibody (Cleaved-Thr472)

Catalog No. ABIN1536131

The Rabbit Polyclonal anti-TGM4 antibody (ABIN1536131) specifically detects TGM4 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TGM4 antibody (Cleaved-Thr472) (ABIN1536131)

Target: TGM4 (Transglutaminase 4 (Prostate) (TGM4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGM4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TGM4 Antibody

Binding Specificity: AA 423-472, Cleaved-Thr472

Purpose: Cleaved-GGT4 HC (T472) Antibody

Specificity: Cleaved-GGT4 HC (T472) Polyclonal Antibody detects endogenous levels of fragment of activated GGT4 HC protein resulting from cleavage adjacent to T472.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Gamma-glutamyltransferase 4. AA range:423-472

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TGM4

Target: TGM4 (Transglutaminase 4 (Prostate) (TGM4))

Alternative Name: gamma-Glutamyltransferase 4

Background:

Synonyms: GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, GGT 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7

Background: This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney.The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008],

Gene Name: GGT7

Protein Name: Gamma-glutamyltransferase 7

Molecular Weight: 50 kDa

Gene ID: 2686

OMIM: 612342

UniProt: Q9UJ14