ITGA7 antibody (Cleaved-Glu959)

Catalog No. ABIN1536135

This Rabbit Polyclonal antibody specifically detects ITGA7 in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for ITGA7 antibody (Cleaved-Glu959) (ABIN1536135)

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITGA7 Antibody

Binding Specificity: AA 940-989, Cleaved-Glu959

Purpose: Cleaved-Integrin α7 LC (E959) Antibody

Specificity: Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ITGA7. AA range:940-989

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Alternative Name: ITGA7

Background:

Synonyms: ITGA7, Integrin alpha-7

Background: integrin subunit alpha 7(ITGA7) Homo sapiens The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009],

Gene Name: ITGA7

Protein Name: Integrin alpha-7

Molecular Weight: 25 kDa

Gene ID: 3679

OMIM: 600536

UniProt: Q13683

Pathways: Integrin Complex