CASC5 antibody (C-Term)

Catalog No. ABIN1536748

This Rabbit Polyclonal antibody specifically detects CASC5 in WB. It exhibits reactivity toward Mouse.

Quick Overview for CASC5 antibody (C-Term) (ABIN1536748)

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40173

Product Details anti-CASC5 Antibody

Binding Specificity: AA 1557-1583, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Casc5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CASC5

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Alternative Name: Casc5

Background: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).

Gene ID: 76464

UniProt: Q66JQ7

Pathways: Maintenance of Protein Location, Autophagy