SCO2 antibody (C-Term)
Quick Overview for SCO2 antibody (C-Term) (ABIN1536825)
Target
See all SCO2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 196-224, C-Term
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Predicted Reactivity
- B, M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- SCO2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Expiry Date
- 6 months
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- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
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Alternative Name
- SCO2
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Background
- Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.
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Molecular Weight
- 29810
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Gene ID
- 9997
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NCBI Accession
- NP_001162580, NP_001162581, NP_001162582, NP_005129
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UniProt
- O43819
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Pathways
- Transition Metal Ion Homeostasis, Warburg Effect
Target
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