Fibulin 5 antibody (C-Term)

Catalog No. ABIN1537265

Product Details anti-Fibulin 5 Antibody

Target: Fibulin 5 (FBLN5)

Binding Specificity: AA 393-421, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBLN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the C-terminal region of human FBLN5.

Clone: RB23905

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FBLN5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: FBLN5 (FBLN5 Products)

Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Molecular Weight: 50180

Gene ID: 10516

NCBI Accession: NP_006320

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome