Apoptosis Inhibitor 5 antibody (C-Term)

Catalog No. ABIN1537392

This anti-Apoptosis Inhibitor 5 antibody is a Rabbit Polyclonal antibody detecting Apoptosis Inhibitor 5 in WB. Suitable for Human.

Quick Overview for Apoptosis Inhibitor 5 antibody (C-Term) (ABIN1537392)

Target: Apoptosis Inhibitor 5 (API5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39469

Product Details anti-Apoptosis Inhibitor 5 Antibody

Binding Specificity: AA 482-510, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This API5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human API5.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: API5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: API5

Background: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Molecular Weight: 59005

Gene ID: 8539

NCBI Accession: NP_001136402, NP_001136403, NP_001230676, NP_006586

UniProt: Q9BZZ5

Pathways: Growth Factor Binding