Osteoactivin antibody (C-Term)

Catalog No. ABIN1537450

This Rabbit Polyclonal antibody specifically detects Osteoactivin in WB. It exhibits reactivity toward Human.

Quick Overview for Osteoactivin antibody (C-Term) (ABIN1537450)

Target: Osteoactivin (GPNMB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36977

Product Details anti-Osteoactivin Antibody

Binding Specificity: AA 541-569, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GPNMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human GPNMB.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GPNMB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB

Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 63923

Gene ID: 10457

NCBI Accession: NP_001005340, NP_002501

UniProt: Q14956