Progesterone Receptor antibody (C-Term)
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- Target See all Progesterone Receptor (PGR) Antibodies
- Progesterone Receptor (PGR)
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Binding Specificity
- AA 816-843, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Progesterone Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PGR/PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human PGR/PR.
- Clone
- RB41081
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PGR Primary Antibody
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- Application Notes
- IF: 1:10~50. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- PGR/PR Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Expiry Date
- 6 months
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- Target
- Progesterone Receptor (PGR)
- Alternative Name
- PGR/PR (PGR Products)
- Background
- This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
- Molecular Weight
- 98981
- Gene ID
- 5241
- NCBI Accession
- NP_000917, NP_001189403, NP_001258091
- UniProt
- P06401
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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