FANCB antibody (AA 360-388)

Catalog No. ABIN1538358

The Rabbit Polyclonal anti-FANCB antibody (Clone RB31350) (ABIN1538358) specifically detects FANCB in WB. The antibody is reactive with Human samples.

Quick Overview for FANCB antibody (AA 360-388) (ABIN1538358)

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB31350

Product Details anti-FANCB Antibody

Binding Specificity: AA 360-388

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FANCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human FANCB.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FANCB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for FANCB

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Alternative Name: FANCB

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.

Molecular Weight: 97726

Gene ID: 2187

NCBI Accession: NP_001018123, NP_689846

UniProt: Q8NB91

Pathways: DNA Damage Repair