SH3BP1 antibody (AA 419-446)
Quick Overview for SH3BP1 antibody (AA 419-446) (ABIN1538408)
Target
See all SH3BP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 419-446
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Predicted Reactivity
- M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- SH3BP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Expiry Date
- 6 months
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- SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
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Alternative Name
- SH3BP1
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Background
- SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
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Molecular Weight
- 75713
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Gene ID
- 23616
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NCBI Accession
- NP_061830
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UniProt
- Q9Y3L3
Target
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