NK2 Homeobox 5 antibody (AA 82-111)

Catalog No. ABIN1538648

The Rabbit Polyclonal anti-NK2 Homeobox 5 antibody is suitable to detect NK2 Homeobox 5 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for NK2 Homeobox 5 antibody (AA 82-111) (ABIN1538648)

Target: NK2 Homeobox 5 (NKX2-5)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36777

Product Details anti-NK2 Homeobox 5 Antibody

Binding Specificity: AA 82-111

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NKX2-5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the Central region of human NKX2-5.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: NKX2-5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Alternative Name: NKX2-5

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Molecular Weight: 34918

Gene ID: 1482

NCBI Accession: NP_001159647, NP_001159648, NP_004378

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development