DDX21 antibody (N-Term)

Catalog No. ABIN1539008

There is 1 publication for this product available. The Rabbit Polyclonal anti-DDX21 antibody is suitable to detect DDX21 in samples from Human. It has been validated for WB.

Quick Overview for DDX21 antibody (N-Term) (ABIN1539008)

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX21 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37016

Product Details anti-DDX21 Antibody

Binding Specificity: AA 128-156, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DDX21 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-DDX21 antibody (ABIN1539008)

Smith, Krumpelbeck, Jegga, Prell, Matrka, Kappes, Greis, Ali, Meetei, Wells: "The nuclear DEK interactome supports multi-functionality." in: Proteins, Vol. 86, Issue 1, pp. 88-97, (2018) (PubMed).

Target Details for DDX21

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Alternative Name: DDX21

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

Molecular Weight: 87344

Gene ID: 9188

NCBI Accession: NP_001243839, NP_004719

UniProt: Q9NR30

Pathways: SARS-CoV-2 Protein Interactome