Myosin 9 antibody (pTyr158)

Catalog No. ABIN1539741

Cited in 1 publication. The Rabbit Polyclonal anti-Myosin 9 antibody (Clone RB36361) (ABIN1539741) specifically detects Myosin 9 in DB. The antibody is reactive with Human samples.

Quick Overview for Myosin 9 antibody (pTyr158) (ABIN1539741)

Target: Myosin 9 (MYH9)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB36361

Product Details anti-Myosin 9 Antibody

Binding Specificity: pTyr158

Predicted Reactivity: C, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYH9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y158 of human MYH9.

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Phospho-MYH9-Y158 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-MYH9-Y158 Antibody at -20 °C.

Expiry Date: 6 months

References for anti-Myosin 9 antibody (ABIN1539741)

Almeida, Mesquita, Cruz, Osório, Custódio, Brito, Vingadassalom, Martins, Leong, Holden, Cabanes, Sousa: "Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8383-95, (2015) (PubMed).

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: MYH9

Background: This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Molecular Weight: 226532

Gene ID: 4627

NCBI Accession: NP_002464

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex