BTK antibody (AA 209-239)

Catalog No. ABIN1539915

The Mouse Monoclonal anti-BTK antibody (Clone 488CT2-1-2) (ABIN1539915) specifically detects BTK in WB. The antibody is reactive with Human samples.

Quick Overview for BTK antibody (AA 209-239) (ABIN1539915)

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BTK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 488CT2-1-2

Product Details anti-BTK Antibody

Binding Specificity: AA 209-239

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This BTK antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 209-239 amino acids from human BTK.

Isotype: IgG1

Application Details

Application Notes: WB: 1:2000~8000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: BTK Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for BTK

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Alternative Name: BTK

Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Molecular Weight: 76281

Gene ID: 695

NCBI Accession: NP_000052

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling