TANK antibody

Catalog No. ABIN155084

The Rabbit Polyclonal anti-TANK antibody is suitable to detect TANK in samples from Human, Mouse and Rat. It has been validated for WB, IHC (p) and IP.

Quick Overview for TANK antibody (ABIN155084)

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TANK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-TANK Antibody

Specificity: This antibody detects TANK.

Purification: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 413 of human TANK

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Mouse small intestine tissue lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Alternative Name: TANK / ITRAF

Background: Members of TRAF family associate with activated TNF-R and CD40 and have been implicated to induce nuclear translocation of NFκB. TANK can bind to all three TRAFs and synergizing with TRAF2 to activate the NFκB signal cascade.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2

Gene ID: 10010

NCBI Accession: NP_001186064

UniProt: Q92844

Pathways: p53 Signaling, TLR Signaling, Activation of Innate immune Response