Cytochrome C antibody

Catalog No. ABIN155088

The Rabbit Polyclonal anti-Cytochrome C antibody (ABIN155088) specifically detects Cytochrome C in WB. The antibody is reactive with Rat samples.

Quick Overview for Cytochrome C antibody (ABIN155088)

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytochrome C Antibody

Specificity: This antibody detects the 12 kDa Cytochrome c.

Purification: Affinity Chromatography

Immunogen: Rat Cytochrome c

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Rat kidney lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Cytochrome C

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Alternative Name: Cytochrome C

Background: Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.Synonyms: CYC, CYCS

Gene ID: 100363502

NCBI Accession: NP_036971

UniProt: P62898

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity