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Fc epsilon RI/FCER1A antibody

FCER1A Reactivity: Human FACS, WB, ELISA, Func Host: Mouse Monoclonal IM-2-NBS020122 unconjugated
Catalog No. ABIN1558257
  • Target See all Fc epsilon RI/FCER1A (FCER1A) Antibodies
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    Reactivity
    • 38
    • 17
    • 2
    • 2
    • 1
    Human
    Host
    • 22
    • 16
    • 9
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 27
    • 24
    • 1
    Monoclonal
    Conjugate
    • 29
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fc epsilon RI/FCER1A antibody is un-conjugated
    Application
    • 28
    • 24
    • 17
    • 17
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)
    Characteristics
    The antibody recognizes an epitope within the a2 domain of the human high affinity IgE receptor (FceRIa). It inhibits binding of IgE to this receptor and is suitable to detect receptors expressed on primary cells and cell lines (e.g mast cells and basophils). It can also be used as weak to moderate cross-linking agent for IgE-independent triggering of effector cells and to detect FceRIa in ELISA and W-blots.
    Purification
    Affinity - purified from cell culture supernatant by Immunoaffinity Chromatography on anti-mouse IgG1 agarose
    Purity
    98 % (Gel Permeation Chromatography)
    Sterility
    Sterile filtered
    Immunogen
    Recombinant human FCER1A
    Clone
    IM-2-NBS020122
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FCER1A Primary Antibody
  • Application Notes
    Can be used for functional mast cell / basophil assays
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS, pH=7.2, 0.1 % NaN3
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8°C. For long term storage, aliquot and store at -20°C or -80°C
  • Target
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    Alternative Name
    FCER1A (FCER1A Products)
    Synonyms
    FCER1A antibody, FCE1A antibody, FcERI antibody, Iger01 antibody, RATIGER01 antibody, Fce1a antibody, Fcr-5 antibody, fcepsilonri antibody, Fc fragment of IgE receptor Ia antibody, Fc receptor, IgE, high affinity I, alpha polypeptide antibody, FCER1A antibody, Fcer1a antibody
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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