CDKN2B antibody (C-Term)

Catalog No. ABIN1590129

This anti-CDKN2B antibody is a Goat Polyclonal antibody detecting CDKN2B in WB and ELISA. Suitable for Human.

Quick Overview for CDKN2B antibody (C-Term) (ABIN1590129)

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CDKN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-CDKN2B Antibody

Binding Specificity: C-Term

Purpose: p15INK4b (isoform 2)

Sequence: RQGARERGAR P

Specificity: This antibody is expected to recognize isoform 2 (NP_511042.1) only.

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 12+14 kDa bands observed in Human Gastrointestinal cancer lysates (calculated MW of 8.1 kDa according to NP_511042.1). The observed 14 kDa cannot represent isoform 1 and therefore it most likely represents another posttranslational modi

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Alternative Name: CDKN2B

Background: CDKN2B, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), CDK4I, INK4B, MTS2, P15, TP15, p15INK4b, CDK inhibitory protein, CDK4B inhibitor, MTS-2, cyclin-dependent kinase 4 inhibitor B, cyclin-dependent kinases 4 and 6 binding protein, multiple t

Gene ID: 1030

NCBI Accession: NP_004927, NP_511042

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases