CRYAB antibody (AA 1-175)

Catalog No. ABIN165394

This Mouse Monoclonal antibody specifically detects CRYAB in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for CRYAB antibody (AA 1-175) (ABIN165394)

Target: CRYAB (Crystallin, alpha B (CRYAB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRYAB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 2E8-

Product Details anti-CRYAB Antibody

Binding Specificity: AA 1-175

Purpose: Human Crystallin alpha B/CRYAB antibody

Purification: Purified

Immunogen: Recombinant human Crystallin alpha B (1-175 aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CRYAB

Target: CRYAB (Crystallin, alpha B (CRYAB))

Alternative Name: Crystallin alpha B/CRYAB

Background: Alpha-Crystallins are composed of two gene products, alpha-Crystallin A and B, for acidic and basic, respectively. alpha-Crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-Crystallin A and B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. alpha-Crystallin B is expressed widely in many tissues and organs and occurs in many neurological diseases.

NCBI Accession: NP_001876