Growth Hormone 1 antibody (AA 27-217)

Catalog No. ABIN165406

This Mouse Monoclonal antibody specifically detects Growth Hormone 1 in WB, ELISA and Neut. It exhibits reactivity toward Human.

Quick Overview for Growth Hormone 1 antibody (AA 27-217) (ABIN165406)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Neutralization (Neut)

Clone: G3H5

Product Details anti-Growth Hormone 1 Antibody

Binding Specificity: AA 27-217

Purpose: Human Growth Hormone 1/GH1 antibody

Purification: Purified

Immunogen: Recombinant human growth hormone (27-217aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Growth Hormone 1/GH1

Background: Human growth hormone (hGH, somatotropin), a protein hormone from the anterior lobe of the pituitary gland, comprises a single polypeptide chain of 191 amino acid residues. The 20 kDa variant form of human growth hormone (20 kDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22 kDa, 191 amino acid) by the deletion of amino acid residues 32-46. The growth hormone amino acid sequence varies considerably between species, and non-primate growth hormones have little activity in man. Main functions of hGH and 20 kDa hGH are the stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues.

NCBI Accession: NP_000506

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process