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NPM1 antibody (AA 81-294)
NPM1
Reactivity: Human
WB, IHC, ELISA, IF, ICC, FACS
Host: Mouse
Monoclonal
5E3
unconjugated
Product Details anti-NPM1 Antibody
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Target
See all NPM1 Antibodies
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Binding Specificity
All epitopes for NPM1 antibodies
AA 81-294
Reactivity
All reactivities for NPM1 antibodies
Human
Host
All hosts for NPM1 antibodies
Mouse
Clonality
All clonalities for NPM1 antibodies
Monoclonal
Conjugate
All conjugates for NPM1 antibodies
This NPM1 antibody is un-conjugated
Application
All applications for NPM1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
Purification
The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Immunogen
Recombinant human NPM (81-294aa) purified from E. coli
Clone
5E3
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Recommended dilution 1:1000(W.B), Recommended dilution 1:100(IHC)
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C,-80 °C
Storage Comment
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target Details for NPM1
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Target
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Alternative Name
NPM1 (NPM1 Products )
Background
Nucleophosmin (NPM, also known as B23, NO38, or numatrin) is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to be indispensable for ribogenesis, cell proliferation, and survival after DNA damage. Nucleophosmin is upregulated in many cancer cells.
NCBI Accession
NP_002511
Pathways
Ribonucleoprotein Complex Subunit Organization , Ribosome Assembly
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