GFM1 antibody (AA 482-751)

Catalog No. ABIN1679983

This Rabbit Polyclonal antibody specifically detects GFM1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for GFM1 antibody (AA 482-751) (ABIN1679983)

Target: GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GFM1 Antibody

Binding Specificity: AA 482-751

Sequence: VYFDTENKET VISGMGELHL EIYAQRLERE YGCPCITGKP KVAFRETITA PVPFDFTHKK QSGGAGQYGK VIGVLEPLDP EDYTKLEFSD ETFGSNIPKQ FVPAVEKGFL DACEKGPLSG HKLSGLRFVL QDGAHHMVDS NEISFIRAGE GALKQALANA TLCILEPIMA VEVVAPNEFQ GQVIAGINRR HGVITGQDGV EDYFTLYADV PLNDMFGYST ELRSCTEGKG EYTMEYSRYQ PCLPSTQEDV INKYLEATGQ LPVKKGKAKN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 482-751 of human GFM1 (NP_079272.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GFM1

Target: GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))

Alternative Name: GFM1

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.,GFM1,COXPD1,EFG,EFG1,EFGM,EGF1,GFM,hEFG1,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Nucleotide metabolism,GFM1

Molecular Weight: 83 kDa/85 kDa

Gene ID: 85476

UniProt: Q96RP9