Glutaminase antibody (AA 610-669)

Catalog No. ABIN1680034

This Rabbit Polyclonal antibody specifically detects Glutaminase in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Glutaminase antibody (AA 610-669) (ABIN1680034)

Target: Glutaminase (GLS)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaminase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Glutaminase Antibody

Binding Specificity: AA 610-669

Sequence: KVNPFPKDRW NNTPMDEALH FGHHDVFKIL QEYQVQYTPQ GDSDNGKENQ TVHKNLDGLL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 610-669 of human Glutaminase (Glutaminase (GLS)) (NP_055720.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutaminase

Target: Glutaminase (GLS)

Alternative Name: GLS

Background: This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.,GLS,AAD20,GAC,GAM,GLS1,KGA,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Warburg Effect,Neuroscience,Cell Type Marker,Neuron marker,GLS

Molecular Weight: 17 kDa/65 kDa/73 kDa

Gene ID: 2744

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect