IL15RA antibody (AA 31-205)

Catalog No. ABIN1680439

This anti-IL15RA antibody is a Rabbit Polyclonal antibody detecting IL15RA in WB and IF. Suitable for Human.

Quick Overview for IL15RA antibody (AA 31-205) (ABIN1680439)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-IL15RA Antibody

Binding Specificity: AA 31-205

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-205 of human IL15RA (NP_002180.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL15RA

Background: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.,IL15RA,CD215,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,CD markers,IL15RA

Molecular Weight: 15-28 kDa

Gene ID: 3601

UniProt: Q13261

Pathways: JAK-STAT Signaling