KAT2B antibody (AA 583-832)

Catalog No. ABIN1680550

This Rabbit Polyclonal antibody specifically detects KAT2B in WB and IF. It exhibits reactivity toward Human.

Quick Overview for KAT2B antibody (AA 583-832) (ABIN1680550)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KAT2B Antibody

Binding Specificity: AA 583-832

Sequence: KGYGTHLMNH LKEYHIKHDI LNFLTYADEY AIGYFKKQGF SKEIKIPKTK YVGYIKDYEG ATLMGCELNP RIPYTEFSVI IKKQKEIIKK LIERKQAQIR KVYPGLSCFK DGVRQIPIES IPGIRETGWK PSGKEKSKEP RDPDQLYSTL KSILQQVKSH QSAWPFMEPV KRTEAPGYYE VIRFPMDLKT MSERLKNRYY VSKKLFMADL QRVFTNCKEY NPPESEYYKC ANILEKFFFS KIKEAGLIDK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 583-832 of human KAT2B (NP_003875.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Alternative Name: KAT2B

Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.,KAT2B,CAF,P/CAF,PCAF,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G2/M DNA Damage Checkpoint,Notch Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,KAT2B

Molecular Weight: 93 kDa

Gene ID: 8850

UniProt: Q92831

Pathways: p53 Signaling, Regulation of Carbohydrate Metabolic Process