LAMP1 antibody (AA 80-280)

Catalog No. ABIN3016286

There is 1 publication for this product available. The Rabbit Polyclonal anti-LAMP1 antibody is suitable to detect LAMP1 in samples from Human. It has been validated for WB and IF.

Quick Overview for LAMP1 antibody (AA 80-280) (ABIN3016286)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LAMP1 Antibody

Binding Specificity: AA 80-280

Sequence: CGKENTSDPS LVIAFGRGHT LTLNFTRNAT RYSVQLMSFV YNLSDTHLFP NASSKEIKTV ESITDIRADI DKKYRCVSGT QVHMNNVTVT LHDATIQAYL SNSSFSRGET RCEQDRPSPT TAPPAPPSPS PSPVPKSPSV DKYNVSGTNG TCLLASMGLQ LNLTYERKDN TTVTRLLNIN PNKTSASGSC GAHLVTLELH S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human LAMP1 (NP_005552.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-LAMP1 antibody (ABIN3016286)

Deng, Pan, Cheng, Liu, Zhang, Zhang, Xu: "Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1862, Issue 3, pp. 337-350, (2017) (PubMed).

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: LAMP1

Background: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.,LAMP1,CD107a,LAMPA,LGP120,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,Neuron marker,Growth Cone,LAMP1

Molecular Weight: 38 kDa/44 kDa

Gene ID: 3916

UniProt: P11279

Pathways: Autophagy