CA9 antibody
Quick Overview for CA9 antibody (ABIN1680827)
Target
See all CA9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Carbonic Anhydrase 9 (CA9/G250)
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CA9 (Carbonic Anhydrase IX (CA9))
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Alternative Name
- CA9
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Background
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014],CAIX, MN,Cancer,Cardiovascular,Endocrine & Metabolism,Hypoxia,Signal Transduction,CA9
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Molecular Weight
- 50 kDa
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Gene ID
- 768
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UniProt
- Q16790
Target
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