MUSK antibody (AA 424-783)

Catalog No. ABIN1680930

The Rabbit Polyclonal anti-MUSK antibody has been validated for WB. It is suitable to detect MUSK in samples from Human.

Quick Overview for MUSK antibody (AA 424-783) (ABIN1680930)

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUSK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUSK Antibody

Binding Specificity: AA 424-783

Sequence: LTITTLYCCR RRKQWKNKKR ESAAVTLTTL PSELLLDRLH PNPMYQRMPL LLNPKLLSLE YPRNNIEYVR DIGEGAFGRV FQARAPGLLP YEPFTMVAVK MLKEEASADM QADFQREAAL MAEFDNPNIV KLLGVCAVGK PMCLLFEYMA YGDLNEFLRS MSPHTVCSLS HSDLSMRAQV SSPGPPPLSC AEQLCIARQV AAGMAYLSER KFVHRDLATR NCLVGENMVV KIADFGLSRN IYSADYYKAN ENDAIPIRWM PPESIFYNRY TTESDVWAYG VVLWEIFSYG LQPYYGMAHE EVIYYVRDGN ILSCPENCPV ELYNLMRLCW SKLPADRPSF TSIHRILERM CERAEGTVSV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 424-783 of human MUSK (NP_001159752.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Alternative Name: MUSK

Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.,MUSK,CMS9,FADS,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,MUSK

Molecular Weight: 86 kDa/87 kDa/97 kDa

Gene ID: 4593

UniProt: O15146

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development