ZYX antibody

Catalog No. ABIN1682627

The Rabbit Monoclonal anti-ZYX antibody is suitable to detect ZYX in samples from Human. It has been validated for WB and IF.

Quick Overview for ZYX antibody (ABIN1682627)

Target: ZYX (Zyxin (ZYX))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ZYX antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ZYX Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Zyxin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZYX

Target: ZYX (Zyxin (ZYX))

Alternative Name: ZYX

Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008],ESP-2, HED-2,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,Neuroscience,RNA Binding,Signal Transduction,Transcription Factors,ZYX

Molecular Weight: 78 kDa

Gene ID: 7791

UniProt: Q15942