MIB1 antibody
Quick Overview for MIB1 antibody (ABIN1682649)
Target
See all MIB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human MIB1/DIP1
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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Alternative Name
- MIB1
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Background
- This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013],DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6,Cell Biology & Developmental Biology,Notch Signaling Pathway,Signal Transduction,Stem Cells,MIB1
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Molecular Weight
- 110 kDa
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Gene ID
- 57534
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UniProt
- Q86YT6
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Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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