XRCC1 antibody

Catalog No. ABIN1682933

The Rabbit Monoclonal anti-XRCC1 antibody has been validated for WB. It is suitable to detect XRCC1 in samples from Human.

Quick Overview for XRCC1 antibody (ABIN1682933)

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This XRCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-XRCC1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human XRCC1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for XRCC1

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Alternative Name: XRCC1

Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],RCC,Cancer,DNA Damage & Repair,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Nucleotide metabolism,Nucleotide metabolism_Purine and pyrimidine synthesis,XRCC1

Molecular Weight: 90 kDa

Gene ID: 7515

UniProt: P18887

Pathways: DNA Damage Repair