Recombinant Thrombomodulin antibody (AA 17-515)

Catalog No. ABIN7795643

This Rabbit Monoclonal antibody specifically detects Thrombomodulin in WB, IHC, IP, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant Thrombomodulin antibody (AA 17-515) (ABIN7795643)

Target: Thrombomodulin (THBD)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: BLR253L

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 17-515

Purpose: Rabbit anti-Thrombomodulin Recombinant Monoclonal Antibody [BLR253L]

Purification: Purified

Immunogen: Residues 17-515 (ECD)

Isotype: IgG

Application Details

Application Notes: Flow-Cyt,Live or cells fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.25 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,12 μL/mg lysate ,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: Thrombomodulin

Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07204].

Gene ID: 7056

UniProt: P07204