TRIOBP antibody (AA 180-310)

Catalog No. ABIN1683149

The Rabbit Polyclonal anti-TRIOBP antibody has been validated for WB and IHC. It is suitable to detect TRIOBP in samples from Human.

Quick Overview for TRIOBP antibody (AA 180-310) (ABIN1683149)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIOBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIOBP Antibody

Binding Specificity: AA 180-310

Sequence: DVTKLSDSNK ENALHSYSTQ KGPLKAGEQR AGSEVISRGG PRKADGQRQA LDYVELSPLT QASPQRARTP ARTPDRLAKQ EELERDLAQR SEERRKWFEA TDSRTPEVPA GEGPRRGLGA PLTEDQQNRL S

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-310 of human TRIOBP (NP_008963.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIOBP

Background: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).,TRIOBP,DFNB28,HRIHFB2122,TAP68,TARA,dJ37E16.4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience,TRIOBP

Molecular Weight: 47 kDa/68 kDa/74 kDa/125 kDa/243 kDa/250 kDa/261 kDa

Gene ID: 11078

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization