CHRNA5 antibody (AA 23-240)
Quick Overview for CHRNA5 antibody (AA 23-240) (ABIN3022469)
Target
See all CHRNA5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 23-240
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Sequence
- RCGLAGAAGG AQRGLSEPSS IAKHEDSLLK DLFQDYERWV RPVEHLNDKI KIKFGLAISQ LVDVDEKNQL MTTNVWLKQE WIDVKLRWNP DDYGGIKVIR VPSDSVWTPD IVLFDNADGR FEGTSTKTVI RYNGTVTWTP PANYKSSCTI DVTFFPFDLQ NCSMKFGSWT YDGSQVDIIL EDQDVDKRDF FDNGEWEIVS ATGSKGNRTD SCCWYPYV
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 23-240 of human CHRNA5 (NP_000736.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CHRNA5 (Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))
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Alternative Name
- CHRNA5
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Background
- The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).,CHRNA5,LNCR2,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA5
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Molecular Weight
- 53 kDa
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Gene ID
- 1138
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UniProt
- P30532
Target
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