IL6RA antibody (Internal Region)

Catalog No. ABIN1686786

This anti-IL6RA antibody is a Goat Polyclonal antibody detecting IL6RA in ELISA. Suitable for Mouse.

Quick Overview for IL6RA antibody (Internal Region) (ABIN1686786)

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This IL6RA antibody is un-conjugated

Application: ELISA

Grade: Recent

Product Details anti-IL6RA Antibody

Binding Specificity: Internal Region

Purpose: Il6ra (mouse)

Sequence: YLLQFQLRYR PVWSK

Specificity: This antibody is expected to recognize all reported isoforms (NP_000556.1, NP_852004.1). The sequence of the immunizing peptide corresponds with a part of the extracellular domain.

Cross-Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Preliminary experiments in Mouse Spleen and Thymus lysates and in lysates of cell lines NIH3T3 and NSO gave no specific signal but low background (at antibody concentration up to 1 μg/mL). We would appreciate any feedback from people in the

Peptide ELISA: antibody detection limit dilution 1:2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for IL6RA

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Alternative Name: Il6ra

Background: Il6ra, interleukin 6 receptor, alpha, CD126, IL-6R, Il6r, MGC30256, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6R

Gene ID: 16194, 24499

NCBI Accession: NP_034689

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints