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IL6RA antibody (AA 351-460) (Biotin)

This Rabbit Polyclonal antibody specifically detects IL6RA in IHC (fro) and IHC (p). It exhibits reactivity toward Mouse.
Catalog No. ABIN734695
$451.08
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 16 to 20 Business Days

Quick Overview for IL6RA antibody (AA 351-460) (Biotin) (ABIN734695)

Target

See all IL6RA Antibodies
IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Reactivity

  • 20
  • 4
  • 1
Mouse

Host

  • 18
  • 3
  • 1
  • 1
  • 1
Rabbit

Clonality

  • 18
  • 6
Polyclonal

Conjugate

  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL6RA antibody is conjugated to Biotin

Application

  • 17
  • 14
  • 14
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 15
    • 3
    • 1
    • 1
    • 1
    AA 351-460

    Purpose

    IL-6R alpha Polyclonal Antibody, Biotin Conjugated

    Cross-Reactivity

    Human

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from mouse IL-6R alpha

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

    Alternative Name

    IL-6R alpha

    Background

    Synonyms: Il6r, CD126, IL-6R, Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Il6ra

    Background: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.

    Gene ID

    16194

    UniProt

    P22272

    Pathways

    JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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