SIRT2 antibody (AbBy Fluor® 555)

Catalog No. ABIN1696771

This Rabbit Polyclonal antibody specifically detects SIRT2 in IF. It exhibits reactivity toward Human.

Quick Overview for SIRT2 antibody (AbBy Fluor® 555) (ABIN1696771)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT2 antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (IF)

Product Details anti-SIRT2 Antibody (AbBy Fluor® 555)

Purpose: SIRT2 Polyclonal Antibody, AbBy Fluor-555 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SIRT2

Isotype: IgG

Application Details

Application Notes: IF(IF=1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Alternative Name: Sirt2

Background:

Synonyms: FLJ35621, FLJ37491, NAD dependent deacetylase sirtuin 2, NAD-dependent deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, Silencing information regulator 2 like, Silent information regulator 2, Silent mating type information regulation 2, Silent mating type information regulation 2 homolog, SIR 2, SIR2, SIR2 like, SIR2 like protein 2, Sir2 related protein type 2, SIR2-like protein 2, SIR2L, SIR2L2, SIRT 2, SIRT2, SIRT2_HUMAN, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), Sirtuin 2, Sirtuin type 2, Sirtuin2.

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Gene ID: 22933

UniProt: Q8IXJ6