GCN1L1 antibody (AA 751-850) (AbBy Fluor® 555)

Catalog No. ABIN1697418

The AbBy Fluor® 555-conjugated Rabbit Polyclonal anti-GCN1L1 antibody (ABIN1697418) specifically detects GCN1L1 in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for GCN1L1 antibody (AA 751-850) (AbBy Fluor® 555) (ABIN1697418)

Target: GCN1L1 (GCN1 General Control of Amino-Acid Synthesis 1-Like 1 (Yeast) (GCN1L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCN1L1 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GCN1L1 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 751-850

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gcn1l1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GCN1L1

Target: GCN1L1 (GCN1 General Control of Amino-Acid Synthesis 1-Like 1 (Yeast) (GCN1L1))

Alternative Name: Gcn1l1

Background:

Synonyms: GCN1, GCN1 general control of amino acid synthesis yeast homolog like, GCN1 general control of amino acid synthesis 1 yeast like 1, GCN1 general control of amino acid synthesis 1 like 1, GCN1 general control of amino acid synthesis 1 like 1 yeast, GCN1 like protein 1, GCN1L, HsGCN1, GCN1L_HUMAN.

Background: GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 10985